Xu-Feng Huang Selected Research

Weight Gain

1/2020	Olanzapine-Induced Activation of Hypothalamic Astrocytes and Toll-Like Receptor-4 Signaling via Endoplasmic Reticulum Stress Were Related to Olanzapine-Induced Weight Gain.
1/2020	Olanzapine increases AMPK-NPY orexigenic signaling by disrupting H1R-GHSR1a interaction in the hypothalamic neurons of mice.
1/2019	Olanzapine-induced endoplasmic reticulum stress and inflammation in the hypothalamus were inhibited by an ER stress inhibitor 4-phenylbutyrate.
11/2018	Obesity, altered oxidative stress, and clinical correlates in chronic schizophrenia patients.
1/2018	Liraglutide prevents metabolic side-effects and improves recognition and working memory during antipsychotic treatment in rats.
11/2017	Time-dependent effects of olanzapine treatment on the expression of histidine decarboxylase, H1 and H3 receptor in the rat brain: The roles in olanzapine-induced obesity.
1/2017	Time-dependent changes and potential mechanisms of glucose-lipid metabolic disorders associated with chronic clozapine or olanzapine treatment in rats.
4/2016	Ameliorating antipsychotic-induced weight gain by betahistine: Mechanisms and clinical implications.
1/2015	Chronic betahistine co-treatment reverses olanzapine's effects on dopamine D₂ but not 5-HT2A/2C bindings in rat brains.
12/2014	Effects of olanzapine on the elevation of macrophage infiltration and pro-inflammatory cytokine expression in female rats.

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Xu-Feng Huang Research Topics

Disease

93	Schizophrenia (Dementia Praecox) 01/2022 - 03/2004
57	Obesity 01/2021 - 07/2003
34	Body Weight (Weight, Body) 01/2020 - 04/2005
32	Weight Gain 01/2020 - 08/2006
27	Inflammation (Inflammations) 01/2022 - 01/2011
19	Cognitive Dysfunction 11/2021 - 02/2009
14	Mental Disorders (Mental Disorder) 01/2020 - 03/2004
12	AIDS-Related Complex (ARC) 01/2020 - 06/2002
8	Neuroinflammatory Diseases 01/2022 - 10/2016
8	Hyperphagia (Overeating) 01/2020 - 03/2011
6	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2021 - 03/2009
5	Psychotic Disorders (Schizoaffective Disorder) 01/2022 - 11/2014
5	Glucose Intolerance 05/2018 - 01/2014
5	Insulin Resistance 05/2018 - 12/2013
5	Necrosis 08/2016 - 01/2011
5	Colonic Neoplasms (Colon Cancer) 06/2011 - 07/2009
4	Bipolar Disorder (Manic Depressive Psychosis) 01/2019 - 03/2004
4	Metabolic Syndrome (Dysmetabolic Syndrome X) 12/2018 - 02/2012
4	Type 2 Diabetes Mellitus (MODY) 04/2017 - 12/2013
4	Weight Loss (Weight Reduction) 09/2014 - 12/2009
3	Neoplasms (Cancer) 01/2021 - 08/2009
3	Alzheimer Disease (Alzheimer's Disease) 01/2021 - 04/2018
3	Morbid Obesity 01/2020 - 06/2013
3	Diabetes Mellitus 01/2017 - 02/2012
3	Carcinogenesis 06/2011 - 06/2009
3	Overweight 04/2010 - 10/2009
2	Tardive Dyskinesia 12/2021 - 03/2015
2	Neurodevelopmental Disorders 10/2019 - 01/2017

Drug/Important Bio-Agent (IBA)

48	Antipsychotic Agents (Antipsychotics)IBA 12/2021 - 06/2008
35	Olanzapine (Zyprexa)FDA Link 08/2021 - 05/2007
22	Proteins (Proteins, Gene)FDA Link 11/2021 - 02/2008
21	Messenger RNA (mRNA)IBA 01/2022 - 06/2002
16	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2022 - 01/2007
14	Pharmaceutical PreparationsIBA 12/2020 - 02/2007
13	Insulin (Novolin)FDA Link 01/2021 - 10/2009
13	Histamine H1 Receptors (Histamine H1 Receptor)IBA 01/2020 - 06/2008
12	Glucose (Dextrose)FDA LinkGeneric 10/2018 - 01/2010
10	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2021 - 06/2015
10	LeptinIBA 09/2020 - 06/2002
9	Clozapine (Clozaril)FDA LinkGeneric 01/2019 - 02/2010
9	Aripiprazole (Abilify)FDA Link 01/2018 - 06/2008
9	Neuregulin-1 (Neuregulin 1)IBA 01/2017 - 08/2009
9	bardoxolone methylIBA 08/2016 - 01/2014
8	Neuropeptide YIBA 01/2020 - 07/2003
8	Phencyclidine (Angel Dust)IBA 10/2019 - 02/2009
8	N-Methylaspartate (NMDA)IBA 01/2018 - 02/2009
7	Haloperidol (Haldol)FDA LinkGeneric 12/2021 - 06/2008
7	Cholinergic Agents (Cholinergics)IBA 04/2018 - 03/2004
6	gamma-Aminobutyric Acid (GABA)IBA 12/2019 - 07/2006
6	CannabinoidsIBA 12/2019 - 07/2006
6	Histamine (Histamine Dihydrochloride)FDA Link 11/2017 - 02/2010
6	Interleukin-6 (Interleukin 6)IBA 08/2016 - 06/2009
6	Betahistine (Serc)IBA 04/2016 - 09/2012
5	CannabidiolIBA 01/2021 - 08/2010
5	CytokinesIBA 01/2021 - 01/2015
5	Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA 09/2020 - 04/2005
5	Risperidone (Risperdal Consta)FDA LinkGeneric 01/2020 - 12/2012
5	CB1 Cannabinoid Receptor (CB1 Receptor)IBA 12/2019 - 07/2006
5	Neurotransmitter Agents (Neurotransmitter)IBA 12/2019 - 07/2005
5	Glutamic Acid (Glutamate)FDA Link 12/2019 - 07/2006
5	Histamine H3 Receptors (Histamine H3 Receptor)IBA 11/2017 - 02/2010
5	Dopamine (Intropin)FDA LinkGeneric 01/2017 - 04/2005
4	GlucansIBA 01/2022 - 07/2011
4	AntioxidantsIBA 11/2020 - 08/2014
4	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 09/2020 - 07/2005
4	Poly I-CIBA 12/2019 - 11/2016
4	LipidsIBA 01/2017 - 02/2014
4	metabotropic glutamate receptor 2IBA 04/2016 - 05/2011
4	Peptides (Polypeptides)IBA 03/2015 - 10/2009
4	PirenzepineIBA 05/2012 - 03/2004
4	Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA 02/2009 - 03/2004
3	EnzymesIBA 01/2022 - 01/2012
3	4-phenylbutyric acid (Buphenyl)FDA Link 08/2021 - 01/2019
3	Neuroprotective AgentsIBA 01/2021 - 06/2016
3	EndocannabinoidsIBA 12/2019 - 11/2007
3	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2019 - 01/2007
3	LipopolysaccharidesIBA 01/2019 - 10/2016
3	Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA 01/2018 - 11/2014
3	Dizocilpine Maleate (Dizocilpine)IBA 01/2018 - 08/2005
3	RimonabantIBA 06/2016 - 11/2007
3	Metabotropic Glutamate 5 ReceptorIBA 08/2015 - 05/2013
3	Therapeutic UsesIBA 01/2015 - 06/2012
3	AMP-Activated Protein KinasesIBA 12/2014 - 04/2014
3	Pro-Opiomelanocortin (Proopiomelanocortin)IBA 10/2014 - 12/2009
3	Hormones (Hormone)IBA 05/2014 - 04/2010
3	GhrelinIBA 05/2014 - 05/2012
3	(1-3)(1-4)- beta-glucanIBA 04/2010 - 10/2009
3	Cannabinoid Receptors (Cannabinoid Receptor)IBA 09/2008 - 07/2006
2	Dietary Fiber FDA Link 11/2021 - 11/2018
2	Neural Cell Adhesion Molecules (Neural Cell Adhesion Molecule)IBA 12/2020 - 01/2018
2	Tight Junction ProteinsIBA 03/2020 - 01/2019
2	5-HT2C Serotonin ReceptorIBA 01/2020 - 08/2004
2	Dopamine D2 Receptors (Dopamine D2 Receptor)IBA 01/2020 - 01/2019
2	Uric Acid (Urate)IBA 01/2019 - 12/2018
2	EndotoxinsIBA 01/2019 - 04/2018
2	Superoxide DismutaseIBA 11/2018 - 11/2018
2	Triglycerides (Triacylglycerol)IBA 11/2018 - 02/2014

Therapy/Procedure

11	Therapeutics 01/2021 - 12/2010
4	Oral Administration 01/2020 - 03/2015
3	Drug Therapy (Chemotherapy) 11/2018 - 02/2008